Products for Research Use Only
RegisterLogin

NQTrp

CAT: 0013-GTR19202490-05Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19202490-05Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NQTrp is a small molecule inhibitor that suppresses tau protein aggregation and exhibits broad anti-amyloidogenic activity. It is utilized in Alzheimer's disease research for in vitro and in vivo studies investigating tauopathy mechanisms and potential therapeutic interventions.
CAS Number
185351-19-3
Product Name Alternative
Aggregation, amyloidogenic, NQTrp, Inhibitor, inhibit, MicrotubuleAssociated, Microtubule Associated, Microtubule/Tubulin, fibrils, hexapeptide, Tau Protein, γD-crystallin
Field of Research
Signal Transduction
Purity
98.35% (May vary between batches)
Solubility
DMSO:125 mg/mL (346.88 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.1 mM)
Smiles
OC (=O) [C@H] (Cc1c[nH]c2ccccc12) NC1=CC (=O) c2ccccc2C1=O
Molecular Formula
C21H16N2O4
Molecular Weight
360.36
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1,4-naphthoquinon-2-yl-L-tryptophan

1,4-naphthoquinon-2-yl-L-tryptophan is an organic molecular entity. It has a role as a protein aggregation inhibitor.

CAS Number185351-19-3
PubChem CID56605052
IUPAC Name(2S)-2-[(1,4-dioxonaphthalen-2-yl)amino]-3-(1H-indol-3-yl)propanoic acid
Molecular FormulaC21H16N2O4
Molecular Weight360.4
XLogP3.4
Topological Polar Surface Area99.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count27
Formal Charge0
Complexity659
SMILES
C1=CC=C2C(=C1)C(=O)C=C(C2=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)O
InChI
InChI=1S/C21H16N2O4/c24-19-10-17(20(25)15-7-2-1-6-14(15)19)23-18(21(26)27)9-12-11-22-16-8-4-3-5-13(12)16/h1-8,10-11,18,22-23H,9H2,(H,26,27)/t18-/m0/s1
InChIKey
DZZUYZXINNHEGM-SFHVURJKSA-N
Chemical Structure
2D Structure
2D structure of 1,4-naphthoquinon-2-yl-L-tryptophan
CAS: 185351-19-3
CID: 56605052
Formula: C21H16N2O4
MW: 360.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight360.4
XLogP33.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass360.11100700
Monoisotopic Mass360.11100700
Topological Polar Surface Area99.3 Ų
Heavy Atom Count27
Formal Charge0
Complexity659
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
563305NQTrp
BA8422-5Cl-NQTrp

Popular Products