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Dichloromethotrexate

CAT: 0013-GTR19199300-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19199300-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dichloromethotrexate is a dihydrofolate reductase (DHFR) inhibitor that blocks nucleotide synthesis, thereby suppressing DNA/RNA production. It is hepatically metabolized and excreted. This small molecule is used in biochemical research to study antifolate mechanisms, cell proliferation, and has been investigated in experimental oncology models.
CAS Number
528-74-5
Smiles
NC=1C2=C (N=CC (CN (C) C3=C (Cl) C=C (C (N[C@@H] (CCC (O) =O) C (O) =O) =O) C=C3Cl) =N2) N=C (N) N1
Molecular Formula
C20H20Cl2N8O5
Molecular Weight
523.33
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T25324-01Dichloromethotrexate

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