Products for Research Use Only
RegisterLogin

EMD57033

CAT: 0013-GTR19199263-03Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19199263-03Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
EMD57033 is a small molecule Ca2+ sensitizer that binds to cardiac troponin C, enhancing myofilament calcium sensitivity and contractile force. It is utilized in cardiovascular research to study contractility mechanisms in both in vitro assays and in vivo models of heart failure.
CAS Number
147527-31-9
Product Name Alternative
CalciumChannel, (+) -EMD 57033, Calcium Channel, Cardiac troponin C, CarbonicAnhydrase, Carbonic Anhydrase, EMD 57033, EMD57033, EMD-57033
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
97.24% (May vary between batches)
Solubility
DMSO:50 mg/mL (117.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.7 mM)
Smiles
O=C (C1=CC (OC) =C (C=C1) OC) N2C3=CC=C (C ([C@H] (S4) C) =NNC4=O) C=C3CCC2
Molecular Formula
C22H23N3O4S
Molecular Weight
425.5
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Emd 53998

EMD 53998 is racemic; EMD 57439 is the (-)-isomer; EMD 57033 is the (+)-isomer

CAS Number147527-31-9
PubChem CID187079
IUPAC Name5-[1-(3,4-dimethoxybenzoyl)-3,4-dihydro-2H-quinolin-6-yl]-6-methyl-3,6-dihydro-1,3,4-thiadiazin-2-one
Molecular FormulaC22H23N3O4S
Molecular Weight425.5
XLogP3.8
Topological Polar Surface Area106
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count30
Formal Charge0
Complexity687
SMILES
CC1C(=NNC(=O)S1)C2=CC3=C(C=C2)N(CCC3)C(=O)C4=CC(=C(C=C4)OC)OC
InChI
InChI=1S/C22H23N3O4S/c1-13-20(23-24-22(27)30-13)15-6-8-17-14(11-15)5-4-10-25(17)21(26)16-7-9-18(28-2)19(12-16)29-3/h6-9,11-13H,4-5,10H2,1-3H3,(H,24,27)
InChIKey
IZLRMTJLQCLMKF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Emd 53998
CAS: 147527-31-9
CID: 187079
Formula: C22H23N3O4S
MW: 425.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight425.5
XLogP33.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass425.14092740
Monoisotopic Mass425.14092740
Topological Polar Surface Area106 Ų
Heavy Atom Count30
Formal Charge0
Complexity687
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19215579-01EMD57439

Alternative Products

CatalogName
MBS5775104EMD57033

Popular Products