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JC124

CAT: 0013-GTR19199112-06Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19199112-06Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JC124 is a selective small molecule inhibitor of the NLRP3 inflammasome. It demonstrates neuroprotective and anti-inflammatory effects, making it a valuable research tool for studying NLRP3-driven pathologies in models of neurodegenerative and inflammatory diseases both in vitro and in vivo.
CAS Number
1638611-48-9
Product Name Alternative
JC124, JC-124, JC 124, NLRP3
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
98.54% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.06 mM) ; DMSO:225 mg/mL (587.68 mM)
Smiles
CNS (=O) (=O) c1ccc (CCNC (=O) c2cc (Cl) ccc2OC) cc1
Molecular Formula
C17H19ClN2O4S
Molecular Weight
382.86
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

5-Chloro-2-methoxy-N-(4-(N-methylsulfamoyl)phenethyl)benzamide
CAS Number1638611-48-9
PubChem CID117715670
IUPAC Name5-chloro-2-methoxy-N-[2-[4-(methylsulfamoyl)phenyl]ethyl]benzamide
Molecular FormulaC17H19ClN2O4S
Molecular Weight382.9
XLogP2.8
Topological Polar Surface Area92.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Heavy Atom Count25
Formal Charge0
Complexity529
SMILES
CNS(=O)(=O)C1=CC=C(C=C1)CCNC(=O)C2=C(C=CC(=C2)Cl)OC
InChI
InChI=1S/C17H19ClN2O4S/c1-19-25(22,23)14-6-3-12(4-7-14)9-10-20-17(21)15-11-13(18)5-8-16(15)24-2/h3-8,11,19H,9-10H2,1-2H3,(H,20,21)
InChIKey
LXYPQRJNQPYTQW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-Chloro-2-methoxy-N-(4-(N-methylsulfamoyl)phenethyl)benzamide
CAS: 1638611-48-9
CID: 117715670
Formula: C17H19ClN2O4S
MW: 382.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight382.9
XLogP32.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Exact Mass382.0754060
Monoisotopic Mass382.0754060
Topological Polar Surface Area92.9 Ų
Heavy Atom Count25
Formal Charge0
Complexity529
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
M34086-01JC124

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