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HZ166

CAT: 0013-GTR19197509-03Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19197509-03Size:100 mg
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Description
HZ-166 is a benzodiazepine site ligand that selectively modulates specific GABAA receptor subtypes, acting as a positive allosteric modulator. It is utilized in neuroscience research to study anxiolytic mechanisms and receptor pharmacology in both in vitro binding assays and in vivo behavioral models.
CAS Number
612527-56-7
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
C (OCC) (=O) C1=C2N (C=3C (C (=NC2) C4=CC=CC=N4) =CC (C#C) =CC3) C=N1
Molecular Formula
C21H16N4O2
Molecular Weight
356.38
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

HZ-166
CAS Number612527-56-7
PubChem CID10309028
IUPAC Nameethyl 8-ethynyl-6-pyridin-2-yl-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
Molecular FormulaC21H16N4O2
Molecular Weight356.4
XLogP2.9
Topological Polar Surface Area69.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count27
Formal Charge0
Complexity639
SMILES
CCOC(=O)C1=C2CN=C(C3=C(N2C=N1)C=CC(=C3)C#C)C4=CC=CC=N4
InChI
InChI=1S/C21H16N4O2/c1-3-14-8-9-17-15(11-14)19(16-7-5-6-10-22-16)23-12-18-20(21(26)27-4-2)24-13-25(17)18/h1,5-11,13H,4,12H2,2H3
InChIKey
ZSEDMNMFODMQRD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of HZ-166
CAS: 612527-56-7
CID: 10309028
Formula: C21H16N4O2
MW: 356.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight356.4
XLogP32.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass356.12732577
Monoisotopic Mass356.12732577
Topological Polar Surface Area69.4 Ų
Heavy Atom Count27
Formal Charge0
Complexity639
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA6699-5HZ166

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