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II-B08

CAT: 0013-GTR19197493-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19197493-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
II-B08 is a cell-permeable small molecule inhibitor of SHP2 with an IC50 of 5.5 μM. It effectively suppresses growth factor-induced ERK1/2 phosphorylation and the proliferation of hematopoietic progenitor cells, making it a useful tool for studying oncogenic signaling pathways in both cellular and biochemical assays.
CAS Number
1143579-78-5
Field of Research
Metabolism Research
Smiles
CN1C (=C (C=2C1=CC (O) =C (C (O) =O) C2) C3=CN (CCC (NC4=CC=C (C=C4) C5=CC=CC=C5) =O) N=N3) C6=CC=CC=C6
Molecular Formula
C33H27N5O4
Molecular Weight
557.6
Storage Conditions
-20°C
Notes
For research use only.

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