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J-104132

CAT: 0013-GTR19197441-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19197441-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
J-104132 is a potent and selective dual endothelin receptor antagonist with subnanomolar affinity for both human ETA and ETB receptors. It effectively inhibits ET-1-induced signaling in vitro and demonstrates potent oral and intravenous activity in vivo, protecting against ET-1-induced lethality in animal models, making it a valuable research tool for studying endothelin-mediated pathways.
CAS Number
198279-45-7
Smiles
C (O) (=O) [C@H]1[C@@H] (C=2C ([C@@H]1C=3C=C4C (=CC3) OCO4) =CC=C (CCCC) N2) C5=C (C[C@@H] (C (O) =O) C) C=C (OC) C=C5
Molecular Formula
C31H33NO7
Molecular Weight
531.60
Storage Conditions
-20°C
Notes
For research use only.

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