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Mouse Anti-Human CD51-PE

CAT: 0544-MBS674268-01Size: 100 TestsDry Ice: NoHazardous: No
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CAT#:0544-MBS674268-01Size:100 Tests
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Reactivity
Human
Storage Conditions
The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0. Store at 2-8 °C.
The fluorescein (FITC) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
The R-phycoerythrin (R-PE) is supplied as 100 tests in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze!
Protect conjugated forms from light. Reagents are stable for the period shown on the label if stored as directed.
Specificity
Human CD51
CD51 represents the 150 kDa integrin alpha V chain that associates with integrin beta 3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils and platelets. CD51 is the most promiscuous integrin a subunit; it can form heterodimers with the beta 1 (CD29), beta 3 (CD61), beta 5, beta 6 and beta 8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins, including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.1-4
Short Name
[CD51 (Integrin alpha V)]

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