Mouse Anti-Chicken CD8a-FITC

Mouse Anti-Chicken CD8a-FITC

• CAS Number: 9007-83-4
• NCBI Gene ID: 677754
• Reactivity: Chicken
• Storage Conditions: The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 °C.
  The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
  The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
  The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze!
  Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
  The Cyanine 5 (CY 5) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
  Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
• Specificity: alpha chain (34-kDa) of chicken CD8
  In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two alpha chains, and (ii) a heterodimer of an alpha chain and a beta chain.1 While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8 alpha - and CD8 beta -chains, a relatively large proportion of the CD8+ TCR- gamma delta cells in the spleens of embryos and young chicks express only the alpha -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- gamma delta CD8 alpha beta cells in the chicken that is not found in rodents.1,3 Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow.1,2 MAb CT-8 recognizes the CD8 alpha chain.1
• Other Gene Names: [cd8a; cd8a; MGC136643; zgc:136643]
• Short Name: [CD8 alpha]
• Other Product Names: [CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide; CD8 alpha; CD8 antigen, alpha polypeptide]
• NCBI GI Number: 91176308
• NCBI Accession Number: NP_001035138.1
• NCBI GB Accession Number: NM_001040049.1
• Uniprot Accession Number: Q24JW8