Products for Research Use Only
RegisterLogin

Rat anti-Mouse CD40-BIOT

CAT: 0544-MBS673355-01Size: 0.5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0544-MBS673355-01Size:0.5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Reactivity
Mouse
Storage Conditions
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 °C.
The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze!
The allophycocyanin (APC) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze!
The Spectral Red (SPRD) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze!
The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 °C.
Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
Specificity
Mouse CD40, Mr 45-50 kDa
CD40 is a type I cell surface protein belonging to the tumor necrosis factor superfamily of cell surface receptors. In mice it is expressed on B lineage cells, follicular dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zone of secondary lymphoid organs.^1-5 CD40 first becomes detectable on a subset of small pre-B II cells in bone marrow, with the levels of CD40 expression increasing thereafter during B-cell maturation. Immature B cells (IgM^+IgD^lo B220^lo) express intermediate levels of CD40, whereas mature B cells (IgM^+IgD^hi B220^hi) express high levels.^4 CD40 has a central role in B cell growth and differentiation, and signalling through CD40 in combination with IL-4 reportedly induces immunoglobulin isotype switching and secretion of IgE.^6 The agonistic 1C10 antibody closely resembles gp39/CD40 ligand in its ability to stimulate proliferation of small, resting B lymphocytes in the absence of other cofactors.^2
Short Name
[CD40]
Other Product Names
[CD40]
NCBI GI Number
114053977

Related Products

CatalogName
MBS673369-01Rat Anti-Mouse CD45/LCA-BIOT
MBS673157-01Rat Anti-Mouse CD4/L3T4-BIOT
MBS673347-01Rat Anti-Mouse CD38-BIOT
MBS673238-01Rat Anti-Mouse CD19-BIOT
MBS673232-01Rat Anti-Mouse CD18-BIOT
MBS673039-01Rat Anti-Mouse IgA-BIOT
MBS673011-01Rat Anti-Mouse IgE-BIOT
MBS670521-01Rat Anti-Mouse CD5-BIOT
MBS673746-01Mouse Anti-Rat IgG2a-BIOT
MBS673339-01Rat Anti-Mouse CD38-BIOT

Alternative Products

CatalogName
1645-08Rat anti-Mouse CD40-BIOT
1400-08Mouse Anti-Phosphotyrosine-BIOT
1576-08Mouse Anti-Mouse CD19-BIOT
1775-08Rat Anti-Mouse BiP-BIOT
1809-08Rat Anti-Mouse CD94-BIOT
1806-08Rat Anti-Mouse CD49b-BIOT
1186-08Rat Anti-Mouse IgG2b-BIOT
1730-08Rat Anti-Mouse CD80-BIOT
1510-08Rat Anti-Mouse CD106-BIOT
1170-08Rat Anti-Mouse Kappa-BIOT

Popular Products