Hamster Anti-Mouse CD28-SPRD

• NCBI Gene ID:

  12487

• Reactivity:

  Mouse

• Storage Conditions:

  The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 °C.
  The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
  The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.
  The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze!
  The allophycocyanin (APC) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing
  The Spectral Red (SPRD) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C. Do not freeze!
  The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 °C.
  Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.

• Specificity:

  CD28 costimulatory receptor, Mr 40 kDa
  CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4^+ and CD8^+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation.^1-4 CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.^5-8

• Other Gene Names:

  [Cd28; Cd28]

• Short Name:

  [CD28]

• Other Product Names:

  [CD28; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28; OTTMUSP00000002157; CD28 antigen]

• NCBI GI Number:

  192485

• Uniprot Accession Number:

  P31041

• CAS Number:

  9007-83-4