Mouse Anti-Human CD23/FCeRII-FITC

• Reactivity:

  Human

• Storage Conditions:

  The fluorescein (FITC) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 °C.

• Specificity:

  Human CD23
  CD23 is a 45 kDa type II integral membrane glycoprotein that is the low affinity receptor for IgE. It also binds to CD21, and the alpha chains of CD11b and CD11c. It is expressed by B cells and monocytes and, weakly, on T cells, follicular dendritic cells, eosinophils, NK cells, Langerhans cells and platelets. It is upregulated in response to B cell activation, CD40 ligation, or in response to IL-4 or IL-13. CD23 is responsible for regulation of IgE synthesis and may play a role in antigen presentation by B cells andfollicular dendritic cells by interacting with CD40.1-7

• Short Name:

  [CD23/FCeRII]

• CAS Number:

  9007-83-4