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(E) -5- (2-Bromovinyl) uracil

CAT: 0013-GTR19192127-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19192127-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(E) -5- (2-Bromovinyl) uracil (BVU) is a metabolite of antiviral nucleosides and a mechanism-based inactivator of dihydropyrimidine dehydrogenase (DPD) . Its irreversible inhibition of DPD enhances the antitumor activity of 5-fluorouracil, as demonstrated in murine leukemia models, making it a research tool for studying fluoropyrimidine pharmacology and combination chemotherapy strategies.
CAS Number
69304-49-0
Field of Research
Cell Biology, Molecular Biology
Smiles
C (=C/Br) \C=1C (=O) NC (=O) NC1
Molecular Formula
C6H5BrN2O2
Molecular Weight
217.02
Storage Conditions
-20°C
Notes
For research use only.

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