Products for Research Use Only
RegisterLogin

Dynapyrazole A

CAT: 0013-GTR19192056-03Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19192056-03Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Dynapyrazole A is a small molecule inhibitor of microtubule-associated dynein motors, with IC50 values of 2.3 and 2.6 μM for dynein 1 and 2, respectively. It also suppresses Hedgehog signaling with an IC50 of 1.9 μM, making it a useful chemical probe for studying cytoskeletal dynamics and developmental signaling pathways in cellular models.
CAS Number
2226517-75-3
Product Name Alternative
Dynamin, Dynapyrazole A
Field of Research
Signal Transduction
Purity
97.44% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (46.23 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.11 mM)
Smiles
Clc1ccc (cc1) C1 (CC1) c1nn2c ([nH]c (=O) c3cc (I) ccc23) c1C#N
Molecular Formula
C20H12ClIN4O
Molecular Weight
486.69
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Dynapyrazole A
CAS Number2226517-75-3
PubChem CID136213044
IUPAC Name2-[1-(4-chlorophenyl)cyclopropyl]-7-iodo-5-oxo-4H-pyrazolo[1,5-a]quinazoline-3-carbonitrile
Molecular FormulaC20H12ClIN4O
Molecular Weight486.7
XLogP4.4
Topological Polar Surface Area70.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Heavy Atom Count27
Formal Charge0
Complexity668
SMILES
C1CC1(C2=CC=C(C=C2)Cl)C3=NN4C5=C(C=C(C=C5)I)C(=O)NC4=C3C#N
InChI
InChI=1S/C20H12ClIN4O/c21-12-3-1-11(2-4-12)20(7-8-20)17-15(10-23)18-24-19(27)14-9-13(22)5-6-16(14)26(18)25-17/h1-6,9H,7-8H2,(H,24,27)
InChIKey
VABPBCMFKJDOHP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Dynapyrazole A
CAS: 2226517-75-3
CID: 136213044
Formula: C20H12ClIN4O
MW: 486.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight486.7
XLogP34.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass485.97444
Monoisotopic Mass485.97444
Topological Polar Surface Area70.7 Ų
Heavy Atom Count27
Formal Charge0
Complexity668
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA4570-100Dynapyrazole-A
6896/5Dynapyrazole A

Popular Products