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OD36

CAT: 0013-GTR19191929-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19191929-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
OD36 is a potent, selective small molecule inhibitor of RIPK2 (IC50 = 5.3 nM) and ALK2 (KD = 37 nM), effectively occupying their ATP-binding sites. It is a valuable research tool for studying innate immunity, heterotopic ossification, and BMP signaling pathways in cellular models.
CAS Number
1638644-62-8
Product Name Alternative
ALK2, OD36, OD-36, OD36 Hydrochloride, OD-36 Hydrochloride, OD 36, RIP kinase, RIPK2, RIPkinase
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.45% (May vary between batches)
Solubility
DMSO:25 mg/mL (75.58 mM)
Smiles
Clc1cc2OCCOCCN=C3Nc4c (cnn4C=C3) -c (c1) c2
Molecular Formula
C16H15ClN4O2
Molecular Weight
330.77
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

6-Chloro-10,11,14,17-tetrahydro-13H-1,16-etheno-4,8-metheno-1H-pyrazolo[3,4-g][1,14,4,6]dioxadiazacyclohexadecine
CAS Number1638644-62-8
PubChem CID135567262
IUPAC Name4-chloro-7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene
Molecular FormulaC16H15ClN4O2
Molecular Weight330.77
XLogP2.5
Topological Polar Surface Area60.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Heavy Atom Count23
Formal Charge0
Complexity402
SMILES
C1COCCOC2=CC(=CC(=C2)C3=C4N=C(N1)C=CN4N=C3)Cl
InChI
InChI=1S/C16H15ClN4O2/c17-12-7-11-8-13(9-12)23-6-5-22-4-2-18-15-1-3-21-16(20-15)14(11)10-19-21/h1,3,7-10H,2,4-6H2,(H,18,20)
InChIKey
KTSDBMVHAKWDRK-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 6-Chloro-10,11,14,17-tetrahydro-13H-1,16-etheno-4,8-metheno-1H-pyrazolo[3,4-g][1,14,4,6]dioxadiazacyclohexadecine
CAS: 1638644-62-8
CID: 135567262
Formula: C16H15ClN4O2
MW: 330.77
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight330.77
XLogP32.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Exact Mass330.0883534
Monoisotopic Mass330.0883534
Topological Polar Surface Area60.7 Ų
Heavy Atom Count23
Formal Charge0
Complexity402
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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CatalogName
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