AZ 5704

CAT: 0013-GTR19191726-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19191726-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

This orally bioavailable, highly potent and selective ATM kinase inhibitor (enzyme IC50 = 0.6 nM) demonstrates >600-fold selectivity and cellular activity (IC50 = 0.33 μM) . It is a valuable research tool for studying DNA damage response and has been shown to potentiate irinotecan's antitumor effects in vivo.

CAS Number

1941214-06-7

Field of Research

Molecular Biology, Signal Transduction

Purity

99.69% (May vary between batches)

Smiles

N ([C@@H] (C) C1=NN (C) C=C1) C=2C3=C (C=C (F) C (=C3) C=4C=CC (COC) =NC4) N=CC2C (N) =O

Molecular Formula

C23H23FN6O2

Molecular Weight

434.47

Storage Conditions

-20°C

Notes

For research use only.

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