Products for Research Use Only

CMC2.24

CAT: 0013-GTR19191372-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19191372-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CMC2.24 is an orally bioavailable tricarbonylmethane compound that inhibits Ras/ERK signaling and zinc-dependent MMPs. It has demonstrated in vivo efficacy in suppressing pancreatic tumorigenesis in mice and shows potential in osteoarthritis models by modulating the NF-κB/HIF-2α pathway to protect cartilage.
CAS Number
1255639-43-0
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction
Smiles
Oc1ccc (\C=C\C (=O) C (C (=O) Nc2ccccc2) C (=O) \C=C\c2ccc (O) cc2) cc1
Molecular Formula
C26H21NO5
Molecular Weight
427.45
Storage Conditions
-20°C
Notes
For research use only.