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RC363

CAT: 0013-GTR19191353-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19191353-02Size:5 mg
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Description
RC363 is a probucol-derived ferroptosis inhibitor that protects HT22 hippocampal cells from glutamate and RSL3-induced toxicity. It functions by enhancing GPX1 levels and GPX activity without directly reducing cellular oxidants. This compound is a valuable research tool for studying ferroptosis mechanisms in neurodegenerative disease models.
CAS Number
2584411-86-7
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2,6-Bis(1,1-dimethylethyl)-4-(2-thienylthio)-phenol
CAS Number2584411-86-7
PubChem CID146673597
IUPAC Name2,6-ditert-butyl-4-thiophen-2-ylsulfanylphenol
Molecular FormulaC18H24OS2
Molecular Weight320.5
XLogP7
Topological Polar Surface Area73.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Heavy Atom Count21
Formal Charge0
Complexity318
SMILES
CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC2=CC=CS2
InChI
InChI=1S/C18H24OS2/c1-17(2,3)13-10-12(21-15-8-7-9-20-15)11-14(16(13)19)18(4,5)6/h7-11,19H,1-6H3
InChIKey
NGMIDNYWQLUYJB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2,6-Bis(1,1-dimethylethyl)-4-(2-thienylthio)-phenol
CAS: 2584411-86-7
CID: 146673597
Formula: C18H24OS2
MW: 320.5
Interactive 3D Structure
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View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight320.5
XLogP37
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass320.12685773
Monoisotopic Mass320.12685773
Topological Polar Surface Area73.8 Ų
Heavy Atom Count21
Formal Charge0
Complexity318
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS5797640RC363

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