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MRIA9

CAT: 0013-GTR19191051-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19191051-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MRIA9 is a potent ATP-competitive inhibitor of pan-Salt-Inducible Kinases (SIK1/2/3) and PAK2/3. It demonstrates potent activity in vitro with IC50 values of 516 nM, 180 nM, and 127 nM against SIK1, SIK2, and SIK3, respectively. This tool compound is valuable for probing SIK signaling in cellular and in vivo models of immunology and cancer.
CAS Number
2750707-05-0
Field of Research
Cell Biology, Signal Transduction
Smiles
C (N1C=2C (C=C (C1=O) C3=C (Cl) C=C (C=C3) C4=C (F) C=CC=N4) =CN=C (NC) N2) [C@@H]5OC[C@@H] (N) CO5
Molecular Formula
C24H22ClFN6O3
Molecular Weight
496.92
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-139253-01MRIA9

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