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HIOC

CAT: 0013-GTR19190901-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19190901-02Size:50 mg
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Description
This small molecule is a selective agonist of the TrkB receptor, demonstrating neuroprotective effects against excitotoxicity. It effectively crosses the blood-brain and blood-retinal barriers, and has been shown in vivo to protect against light-induced retinal degeneration, supporting research in neuroscience and ophthalmology.
CAS Number
314054-36-9
Field of Research
Cell Biology, Signal Transduction
Smiles
C (CNC (=O) C1C (=O) NCCC1) C=2C=3C (NC2) =CC=C (O) C3
Molecular Formula
C16H19N3O3
Molecular Weight
301.34
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-oxopiperidine-3-carboxamide

a TrkB receptor activator and neuroprotective agent; structure in first source

CAS Number314054-36-9
PubChem CID5012758
IUPAC NameN-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-oxopiperidine-3-carboxamide
Molecular FormulaC16H19N3O3
Molecular Weight301.34
XLogP1
Topological Polar Surface Area94.2
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Heavy Atom Count22
Formal Charge0
Complexity429
SMILES
C1CC(C(=O)NC1)C(=O)NCCC2=CNC3=C2C=C(C=C3)O
InChI
InChI=1S/C16H19N3O3/c20-11-3-4-14-13(8-11)10(9-19-14)5-7-18-16(22)12-2-1-6-17-15(12)21/h3-4,8-9,12,19-20H,1-2,5-7H2,(H,17,21)(H,18,22)
InChIKey
ZIMKJLALTRLXJO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-oxopiperidine-3-carboxamide
CAS: 314054-36-9
CID: 5012758
Formula: C16H19N3O3
MW: 301.34
Interactive 3D Structure
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View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight301.34
XLogP31
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass301.14264148
Monoisotopic Mass301.14264148
Topological Polar Surface Area94.2 Ų
Heavy Atom Count22
Formal Charge0
Complexity429
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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