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Coixenolide

CAT: 0804-HY-N12777-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N12777-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Coixenolide can be isolated from coix seeds, and exhibits anti-inflammatory, anti-tumor and pain-reducing activities. Coixenolide stimulates the lung, heart, striated and smooth muscles at low doses, while inhibits at high doses. Coixenolide dilates pulmonary veins and improves pulmonary blood circulation. Coixenolide can also be used as nutraceuticals and functional foods. Coixenolide enhances the prodcutionof mycelia biomass and polysaccharides when added to the media of submerged culture of G. lucidum. Coixenolide affects the synthesis level of phosphoglucose isomerase and α-phosphoglucomutase[1][2].
CAS Number
29066-43-1
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/coixenolide.html
Purity
99.93
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : ≥ 100 mg/mL|THF : 40 mg/mL (ultrasonic)
Smiles
CCCCCC/C=C\CCCCCCCC(O[C@H](C)[C@H](C)OC(CCCCCCCCC/C=C/CCCCCC)=O)=O
Molecular Formula
C38H70O4
Molecular Weight
590.96
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Hu AJ, et al., Ultrasound assisted supercritical fluid extraction of oil and coixenolide from adlay seed. Ultrason Sonochem. 2007 Feb;14 (2) :219-24.|[2]Zhou, H., et al., (2014) . Improved polysaccharide production in submerged culture of Ganoderma lucidum by the addition of coixenolide. Applied biochemistry and biotechnology, 172 (3), 1497–1505.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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