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NPC-15437

CAT: 0013-GTR19190586-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19190586-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NPC-15437 dihydrochloride is a selective, cell-permeable PKC inhibitor (IC50 ~19-23 μM) that does not affect cAMP-dependent or Ca2+/calmodulin-dependent kinases. It serves as a key pharmacological tool for studying PKC signaling in vitro and has been used in research models investigating neuronal function and cardiovascular responses.
CAS Number
141774-20-1
Product Name Alternative
NPC15437, NPC-15437, NPC15437 (hydrochloride), NPC15437 dihydrochloride, NPC 15437, NPC 15437 (hydrochloride)
Field of Research
Epigenetics & Chromatin, Metabolism Research, Signal Transduction
Purity
>98%
Bioactivity
PKC inhibitor
Form
Powder
Solubility
Soluble in Water (up to 10 mg/ml) .
Smiles
NCCCC[C@H] (N) C (NCC1N (CCCC1) C (CCCCCCCCCCCC) =O) =O.Cl.Cl
Molecular Formula
C25H50N4O2 ∙ 2HCl
Molecular Weight
511.61
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(S) -2,6-Diamino-N-[ (1- (1-oxotridecyl) -2-piperidinyl) methyl]hexanamide dihydrochloride hydrate

Chemical Information

NPC-15437 dihydrochloride
CAS Number141774-20-1
PubChem CID16219723
IUPAC Name(2S)-2,6-diamino-N-[(1-tridecanoylpiperidin-2-yl)methyl]hexanamide;dihydrochloride
Molecular FormulaC25H52Cl2N4O2
Molecular Weight511.6
Topological Polar Surface Area101
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count4
Rotatable Bond Count18
Heavy Atom Count33
Formal Charge0
Complexity472
SMILES
CCCCCCCCCCCCC(=O)N1CCCCC1CNC(=O)[C@H](CCCCN)N.Cl.Cl
InChI
InChI=1S/C25H50N4O2.2ClH/c1-2-3-4-5-6-7-8-9-10-11-18-24(30)29-20-15-13-16-22(29)21-28-25(31)23(27)17-12-14-19-26;;/h22-23H,2-21,26-27H2,1H3,(H,28,31);2*1H/t22?,23-;;/m0../s1
InChIKey
RISSBZWRJRRXTD-OLBPYZPGSA-N
Chemical Structure
2D Structure
2D structure of NPC-15437 dihydrochloride
CAS: 141774-20-1
CID: 16219723
Formula: C25H52Cl2N4O2
MW: 511.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight511.6
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count4
Rotatable Bond Count18
Exact Mass510.3467323
Monoisotopic Mass510.3467323
Topological Polar Surface Area101 Ų
Heavy Atom Count33
Formal Charge0
Complexity472
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count3
Compound Is CanonicalizedYes

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