Products for Research Use Only
RegisterLogin

SRTCX1003

CAT: 0013-GTR19196429-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19196429-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SRTCX1003 is a small molecule activator of SIRT1 that attenuates inflammatory signaling by enhancing the deacetylation of the p65 subunit, thereby inhibiting NF-κB transcriptional activity. This mechanism supports its research use in studying inflammation-related pathways in both cellular and animal models.
CAS Number
1203480-86-7
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
C (NC1=NC=CS1) (=O) C2=C3C (N=C (N3) C4=C (OCCN5CCOCC5) C=CC=C4) =CC=C2
Molecular Formula
C23H23N5O3S
Molecular Weight
449.53
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Srtcx1003

a SIRT1 activator; structure in first source

CAS Number1203480-86-7
PubChem CID75124302
IUPAC Name2-[2-(2-morpholin-4-ylethoxy)phenyl]-N-(1,3-thiazol-2-yl)-1H-benzimidazole-4-carboxamide
Molecular FormulaC23H23N5O3S
Molecular Weight449.5
XLogP3
Topological Polar Surface Area121
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count7
Heavy Atom Count32
Formal Charge0
Complexity622
SMILES
C1COCCN1CCOC2=CC=CC=C2C3=NC4=C(C=CC=C4N3)C(=O)NC5=NC=CS5
InChI
InChI=1S/C23H23N5O3S/c29-22(27-23-24-8-15-32-23)17-5-3-6-18-20(17)26-21(25-18)16-4-1-2-7-19(16)31-14-11-28-9-12-30-13-10-28/h1-8,15H,9-14H2,(H,25,26)(H,24,27,29)
InChIKey
BXSJTHFUADFIKS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Srtcx1003
CAS: 1203480-86-7
CID: 75124302
Formula: C23H23N5O3S
MW: 449.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight449.5
XLogP33
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count7
Exact Mass449.15216079
Monoisotopic Mass449.15216079
Topological Polar Surface Area121 Ų
Heavy Atom Count32
Formal Charge0
Complexity622
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19199057-01SRTCX1002

Alternative Products

CatalogName
HY-124240SRTCX1003

Popular Products