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Deoxyhypusine

CAT: 0013-GTR19194738-03Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19194738-03Size:100 mg
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Description
Deoxyhypusine is a crucial intermediate in the post-translational hypusination of eukaryotic initiation factor 5A (eIF5A) . This small molecule is used in biochemical research to study eIF5A function in cell proliferation, differentiation, and viral replication in both cellular and animal models.
CAS Number
82543-85-9
Field of Research
Metabolism Research
Smiles
C (CCNCCCCN) C[C@@H] (C (O) =O) N
Molecular Formula
C10H23N3O2
Molecular Weight
217.31
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Deoxyhypusine

Deoxyhypusine is an L-lysine derivative in which the N6 of the lysine is substituted with a 4-aminobutyl group. It has a role as a human metabolite. It is a L-lysine derivative and a non-proteinogenic L-alpha-amino acid. It is functionally related to a hypusine.

CAS Number82543-85-9
PubChem CID122083
IUPAC Name(2S)-2-amino-6-(4-aminobutylamino)hexanoic acid
Molecular FormulaC10H23N3O2
Molecular Weight217.31
XLogP-2.8
Topological Polar Surface Area101
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count10
Heavy Atom Count15
Formal Charge0
Complexity165
SMILES
C(CCNCCCCN)C[C@@H](C(=O)O)N
InChI
InChI=1S/C10H23N3O2/c11-6-2-4-8-13-7-3-1-5-9(12)10(14)15/h9,13H,1-8,11-12H2,(H,14,15)/t9-/m0/s1
InChIKey
PGPFBXMCOQNMJO-VIFPVBQESA-N
Chemical Structure
2D Structure
2D structure of Deoxyhypusine
CAS: 82543-85-9
CID: 122083
Formula: C10H23N3O2
MW: 217.31
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight217.31
XLogP3-2.8
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count10
Exact Mass217.17902698
Monoisotopic Mass217.17902698
Topological Polar Surface Area101 Ų
Heavy Atom Count15
Formal Charge0
Complexity165
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-121722Deoxyhypusine
479588DOHH (Deoxyhypusine Hydroxylase, Deoxyhypusine Hydroxylase/Monooxygenase)
479315DHPS (Deoxyhypusine Synthase)
MBS645239-01HLRC1 (Deoxyhypusine Hydroxylase, hDOHH, Deoxyhypusine Dioxygenase, Deoxyhypusine Monooxygenase, HEAT-like Repeat-containing Protein 1, DOHH, MGC4293)
245320DHPS (deoxyhypusine Synthase, MIG13)
MBS2033152-01Recombinant Deoxyhypusine Synthase (DHPS)
abx119594-01Deoxyhypusine Synthase (DHPS) Antibody
E15938rELISA Kit For Deoxyhypusine hydroxylase
7-02662Recombinant Human Deoxyhypusine Synthase
abx349202-01Deoxyhypusine Hydroxylase (DOHH) Antibody

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