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Sinitrodil

CAT: 0013-GTR19192627-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19192627-02Size:5 mg
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Description
Sinitrodil (ITF-296) is a soluble guanylate cyclase (sGC) stimulant investigated for treating myocardial ischemia and angina. Research applications include studying its vasodilatory and cardioprotective effects in models of coronary artery disease, both in vitro and in vivo.
CAS Number
143248-63-9
Product Name Alternative
ITF 296, ITF296, ITF-296, Guanylatecyclase, Guanylate cyclase, Sinitrodil
Field of Research
Pharmacology & Drug Discovery
Purity
97.03% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (115.45 mM)
Smiles
O=C1C=2C (OCN1CCON (=O) =O) =CC=CC2
Molecular Formula
C10H10N2O5
Molecular Weight
238.2
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Sinitrodil

Sinitrodil is a small molecule drug. The usage of the INN stem '-dil' in the name indicates that Sinitrodil is a vasodilator. Sinitrodil has a monoisotopic molecular weight of 238.06 Da.

CAS Number143248-63-9
PubChem CID121985
IUPAC Name2-(4-oxo-2H-1,3-benzoxazin-3-yl)ethyl nitrate
Molecular FormulaC10H10N2O5
Molecular Weight238.20
XLogP1.5
Topological Polar Surface Area84.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count17
Formal Charge0
Complexity304
SMILES
C1N(C(=O)C2=CC=CC=C2O1)CCO[N+](=O)[O-]
InChI
InChI=1S/C10H10N2O5/c13-10-8-3-1-2-4-9(8)16-7-11(10)5-6-17-12(14)15/h1-4H,5-7H2
InChIKey
POVFCWQCRHXYAB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Sinitrodil
CAS: 143248-63-9
CID: 121985
Formula: C10H10N2O5
MW: 238.20
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight238.20
XLogP31.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass238.05897142
Monoisotopic Mass238.05897142
Topological Polar Surface Area84.6 Ų
Heavy Atom Count17
Formal Charge0
Complexity304
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
M34710-01Sinitrodil

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