Products for Research Use Only

BX-320

CAT: 0013-GTR19191379-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19191379-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BX-320 is a potent and selective PDK1 inhibitor (IC50=30 nM) that suppresses downstream Akt and p70S6K phosphorylation in vitro. It induces apoptosis and inhibits proliferation in various cancer cell lines and demonstrates in vivo efficacy by reducing lung tumor growth in a mouse metastasis model.
CAS Number
702676-93-5
Field of Research
Signal Transduction
Smiles
CC (C) (C (N) =O) C (=O) NCCCNC1=NC (NC2=CC=CC (NC (=O) N3CCCC3) =C2) =NC=C1Br
Molecular Formula
C23H31BrN8O3
Molecular Weight
547.45
Storage Conditions
-20°C
Notes
For research use only.