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CAY10719

CAT: 0013-GTR19190542-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19190542-02Size:5 mg
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Description
CAY10719 is a potent and selective ABCG2 inhibitor (IC50 = 0.23 μM) that reverses multidrug resistance to chemotherapeutics like SN-38 in vitro. Its ability to suppress ABCG2 ATPase activity makes it a valuable research tool for studying transporter function and overcoming drug efflux in cancer models.
CAS Number
1942919-63-2
Field of Research
Pharmacology & Drug Discovery
Smiles
C (=O) (N1C (C2=C (C=3C (N2) =CC=CC3) CC1) C4=CC (Cl) =C (Cl) C=C4) C5=CC=C (OC) C=C5
Molecular Formula
C25H20Cl2N2O2
Molecular Weight
451.34
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

[1-(3,4-Dichlorophenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-(4-methoxyphenyl)methanone
CAS Number1942919-63-2
PubChem CID132285218
IUPAC Name[1-(3,4-dichlorophenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-(4-methoxyphenyl)methanone
Molecular FormulaC25H20Cl2N2O2
Molecular Weight451.3
XLogP6
Topological Polar Surface Area45.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Heavy Atom Count31
Formal Charge0
Complexity641
SMILES
COC1=CC=C(C=C1)C(=O)N2CCC3=C(C2C4=CC(=C(C=C4)Cl)Cl)NC5=CC=CC=C35
InChI
InChI=1S/C25H20Cl2N2O2/c1-31-17-9-6-15(7-10-17)25(30)29-13-12-19-18-4-2-3-5-22(18)28-23(19)24(29)16-8-11-20(26)21(27)14-16/h2-11,14,24,28H,12-13H2,1H3
InChIKey
AKQFVWUCZTWDKB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of [1-(3,4-Dichlorophenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-(4-methoxyphenyl)methanone
CAS: 1942919-63-2
CID: 132285218
Formula: C25H20Cl2N2O2
MW: 451.3
Interactive 3D Structure
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View on PubChemRaw 3D data

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