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Kigamicin C

CAT: 0013-GTR19190414Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19190414Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kigamicins are antitumor antibiotics with selective cytotoxicity against nutrient-starved pancreatic cancer cells, such as PANC-1, and exhibit antimicrobial activity against Gram-positive bacteria. Kigamicin D demonstrates in vivo efficacy by suppressing pancreatic tumor growth in mouse models, potentially through inhibition of Akt activation under nutrient stress. These compounds also induce necrosis in human myeloma cells while sparing normal lymphocytes.
CAS Number
680571-51-1
Field of Research
Infectious Disease & Virology
Smiles
[H][C@]12Cc3cc4C[C@@]5 (C) OCCN5C (=O) c4c (O) c3-c3c (O) c4c (oc5[C@@H] (O) [C@@H] (C[C@H] (O) c5c4=O) O[C@H]4CC[C@H] (O[C@H]5C[C@@H] (OC) [C@H] (O) [C@@H] (C) O5) [C@@H] (C) O4) c (OCO1) c23
Molecular Formula
C41H47NO16
Molecular Weight
809.818
Storage Conditions
-20°C
Notes
For research use only.

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