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MHC Class 2, I-A, Rt1.Bu

CAT: 0544-MBS633523-01Size: 100 TestsDry Ice: NoHazardous: No
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CAT#:0544-MBS633523-01Size:100 Tests
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Reactivity
Mouse, Rat
Storage Conditions
-20 °C
Specificity
Recognizes a polymorphic determinant of rat Ia antigen (RT1.Bu) present on Lewis, Wistar and AO strain rats, but not RN, DA or PVG/c strains. The antibody crossreacts with mouse strains (MHC haplotypes b and s) and analysis of recombinant mouse strains showed that the determinants mapped to the I-A region. It recognizes Ia antigens on B cell, dendritic cells and certain epithelial cells. It is particularly useful for distinguishing Ia positive cells from different rat strains, eg for recognizing cells of donor origin in bone marrow reconstituted radiation chimeras.
Short Name
[MHC Class 2, I-A, Rt1.Bu]