Melanoma, gp100 (Melanoma Associated Antigen)

• NCBI Gene ID:

  6490

• Reactivity:

  Human

• Storage Conditions:

  May be stored at 4 °C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 °C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 

• Specificity:

  Recognizes a human (pre)melanosomal 100+7kD antigen (glycoprotein). Reacts with melanomas, clear cells sarcomas (melanoma of soft tissue), nevocellular nevi and normal melanocytes. Except for one case of non-Hodgkin's lymphoma in which macrophages were positive, no reactions with other tumors or tissues have been observed.

• Other Gene Names:

  [PMEL; PMEL; P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E; D12S53E; PMEL17; SILV; ME20M; ME20-S; ME20S]

• Short Name:

  [Melanoma, gp100]

• Other Product Names:

  [melanocyte protein PMEL isoform 3 preproprotein; Melanocyte protein PMEL; melanocyte protein PMEL; melanocyte protein mel 17; silver, mouse, homolog of; melanocyte protein Pmel 17; melanosomal matrix protein17; silver locus protein homolog; melanoma-associated ME20 antigen; melanocytes lineage-specific antigen GP100; premelanosome protein; ME20-M; ME20M; Melanocyte protein Pmel 17; Melanocytes lineage-specific antigen GP100; Melanoma-associated ME20 antigen; P1; P100; Premelanosome protein; Silver locus protein homologCleaved into the following 2 chains:M-alpha; Alternative name(s):; 95 kDa melanocyte-specific secreted glycoprotein; P26; Secreted melanoma-associated ME20 antigen]

• NCBI GI Number:

  5902084

• NCBI Accession Number:

  NP_008859.1

• NCBI GB Accession Number:

  NM_006928.4

• Uniprot Accession Number:

  P40967

• CAS Number:

  9007-83-4