Patulin

• UNSPSC Description:

  Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage[1][2][3][4].

• Target Antigen:

  Antibiotic; Apoptosis; Autophagy; Bacterial

• Type:

  Natural Products

• Related Pathways:

  Anti-infection;Apoptosis;Autophagy

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/patulin.html

• Purity:

  99.47

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic;warming)

• Smiles:

  O=C1OC2=CCOC(C2=C1)O

• Molecular Weight:

  154.121

• References & Citations:

  [1]Puel O, et al. Biosynthesis and toxicological effects of patulin. Toxins (Basel). 2010 Apr;2(4):613-31.|[2]Glaser N, et al. Patulin: Mechanism of genotoxicity. Food Chem Toxicol. 2012 May;50(5):1796-801.|[3]Sun M, et al. Patulin Induces Autophagy-Dependent Apoptosis through Lysosomal-Mitochondrial Axis and Impaired Mitophagy in HepG2 Cells. J Agric Food Chem. 2018 Nov 21;66(46):12376-12384.|[4]Glaser N, et al. Patulin: Mechanism of genotoxicity. Food Chem Toxicol. 2012 May;50(5):1796-801.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  149-29-1