Patulin

• Description :

  Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage[1][2][3][4].

• Product Name Alternative :

  Terinin

• UNSPSC :

  12352005

• Hazard Statement :

  H300, H315

• Target :

  Antibiotic; Apoptosis; Autophagy; Bacterial

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Apoptosis; Autophagy

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/patulin.html

• Purity :

  99.94

• Solubility :

  DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic; warming)

• Smiles :

  O=C1OC2=CCOC(C2=C1)O

• Molecular Formula :

  C7H6O4

• Molecular Weight :

  154.12

• Precautions :

  H300, H315

• References & Citations :

  [1]Puel O, et al. Biosynthesis and toxicological effects of patulin. Toxins (Basel) . 2010 Apr;2 (4) :613-31.|[2]Glaser N, et al. Patulin: Mechanism of genotoxicity. Food Chem Toxicol. 2012 May;50 (5) :1796-801.|[3]Sun M, et al. Patulin Induces Autophagy-Dependent Apoptosis through Lysosomal-Mitochondrial Axis and Impaired Mitophagy in HepG2 Cells. J Agric Food Chem. 2018 Nov 21;66 (46) :12376-12384.|[4]Glaser N, et al. Patulin: Mechanism of genotoxicity. Food Chem Toxicol. 2012 May;50 (5) :1796-801.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [149-29-1]