GABA Receptor A, gamma 2 (GAG2)

• NCBI Gene ID:

  2566

• Reactivity:

  Bovine, Human, Mouse, Rat

• Storage Conditions:

  May be stored at 4 °C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 °C. Aliquots are stable for at least 12 months at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

• Specificity:

  Recognizes GABA receptor A, Gama 2. The 30 AA rat control peptide is 100% conserved in bovine, human and mouse GAG2 (2). It is ~80% conserved in chicken GAB2. Significant homology is also seen with rat GAG1 (64%), ratGAG3 (55%). It is not clear if anti-GAG21 actually reacts with other gamma subunits. No significant homology is observed with other GAA subunits (alpha, beta etc.). Antibody crossreactivity of anti-GAG21 in various species has also not been studied.

• Other Gene Names:

  [GABRG2; GABRG2; CAE2; ECA2; GEFSP3]

• Short Name:

  [GABA Receptor A, gamma 2]

• Other Product Names:

  [gamma-aminobutyric acid receptor subunit gamma-2 isoform 2; Gamma-aminobutyric acid receptor subunit gamma-2; gamma-aminobutyric acid receptor subunit gamma-2; OTTHUMP00000160873; OTTHUMP00000160874; OTTHUMP00000224398; OTTHUMP00000224400; GABA(A) receptor subunit gamma-2; gamma-aminobutyric acid (GABA) A receptor, gamma 2; GABA(A) receptor subunit gamma-2]

• NCBI GI Number:

  38788135

• NCBI Accession Number:

  NP_000807.2

• NCBI GB Accession Number:

  NM_000816.3

• Uniprot Accession Number:

  P18507