AEF0117

CAT: 0804-HY-156831-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-156831-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1610878-71-1

UNSPSC Description

AEF0117 is a signaling-specific inhibitor of the cannabinoid receptor 1 (CB1-SSi). AEF0117 plays an important role in Cannabis use disorder (CUD)[1].

Target Antigen

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aef0117.html

Solubility

DMF : 10 mg/mL (ultrasonic)|DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OCC4=CC=C(C=C4)OC)([H])[C@@]5([H])[C@](CC3)([C@H](CC5)C(C)=O)C

Molecular Weight

436.63

References & Citations

[1]Margaret Haney, et al. Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials. Nat Med. 2023 Jun;29(6):1487-1499.

Shipping Conditions

Room Temperature

Clinical Information

Phase 2

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M37258-01	AEF0117

AEF0117

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