Products for Research Use Only
RegisterLogin

5-Aminothalidomide

CAT: 0013-GTR19189112-02Size: 1 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19189112-02Size:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
5-Aminothalidomide is a cereblon (CRBN) E3 ligase ligand utilized in the construction of PROTAC molecules. It enables targeted protein degradation and is widely applied in cancer research and drug discovery, both in vitro and in vivo.
CAS Number
191732-76-0
Product Name Alternative
5-Aminothalidomide, 5amino2 (2,6dioxopiperidin3yl) isoindoline1,3dione, 5 amino 2 (2,6 dioxopiperidin 3 yl) isoindoline 1,3 dione, Cereblon, Ligand for E3 Ligase, LigandforE3Ligase
Field of Research
Pharmacology & Drug Discovery
Purity
99.87% (May vary between batches)
Smiles
O=C1N (C (=O) C=2C1=CC (N) =CC2) C3C (=O) NC (=O) CC3
Molecular Formula
C13H11N3O4
Molecular Weight
273.24
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline
CAS Number191732-76-0
PubChem CID9816958
IUPAC Name5-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Molecular FormulaC13H11N3O4
Molecular Weight273.24
XLogP-0.4
Topological Polar Surface Area110
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Heavy Atom Count20
Formal Charge0
Complexity504
SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)N
InChI
InChI=1S/C13H11N3O4/c14-6-1-2-7-8(5-6)13(20)16(12(7)19)9-3-4-10(17)15-11(9)18/h1-2,5,9H,3-4,14H2,(H,15,17,18)
InChIKey
IICWMVJMJVXCLY-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-5-aminoisoindoline
CAS: 191732-76-0
CID: 9816958
Formula: C13H11N3O4
MW: 273.24
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight273.24
XLogP3-0.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass273.07495584
Monoisotopic Mass273.07495584
Topological Polar Surface Area110 Ų
Heavy Atom Count20
Formal Charge0
Complexity504
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19221943-015,5'-Dimethoxysecoisolariciresinol
GTR19230899-015-LOX-IN-5
GTR180271485.5 Antibody
GTR19235383-01FABP4/5-IN-5
GTR180271505.5 Antibody
GTR180270775.5 Antibody
GTR19182420-015,5'-Dimethoxylariciresinol
GTR19214416-015'-Deoxy-5'-iodo-5-methyluridine
GTR19214414-015'-Azido-5'-deoxy-5-methyluridine
GTR19214415-014',5'-Didehydro-5'-deoxy-5-methyluridine

Alternative Products

CatalogName
HY-W023573-015-Aminothalidomide
T89465-015-Aminothalidomide-cyclohexane
T201399-015-Aminothalidomide-C9-Boc
HY-1685533-Hydroxyazetidine-Cyclohexanol-5-Aminothalidomide
T212074-015-Aminothalidomide-NH-C7-NH2
sc-2627255,5,5-Trifluorovaleronitrile
234404-015,5,5-Trifluoronorvaline
PDA866615,5,5-Trifluoropentanonitrile
JH2382995,5,5-trifluoroleucine
AKA25347-015,5,5-Trifluoropentanal

Popular Products