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SAG dihydrochloride

CAT: 0013-GTR19189039-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19189039-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SAG dihydrochloride is a potent and selective Smoothened (Smo) receptor agonist (EC50 = 3 nM) that activates Hedgehog signaling. It is used in vitro and in vivo to study pathway mechanisms and counteract antagonists like cyclopamine in cancer and developmental biology research.
CAS Number
2702366-44-5
Product Name Alternative
Hedgehog, Smoothened, SAG Dihydrochloride, SAG dihydrochloride, SAG
Field of Research
Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
99.57% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.55 mM) ; DMSO:15 mg/mL (26.64 mM)
Smiles
O=C (C1=C (C2=CC=CC=C2S1) Cl) N ([C@@H]3CC[C@H] (CC3) NC) CC4=CC (C5=CC=NC=C5) =CC=C4.Cl.Cl
Molecular Formula
C28H30Cl3N3OS
Molecular Weight
562.98
Storage Conditions
-20°C
Notes
For research use only.

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