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P53R3

CAT: 0013-GTR19188675-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19188675-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P53R3 is a potent small molecule reactivator of mutant p53, restoring DNA binding and transcriptional activity to common hotspot mutants like R175H, R248W, and R273H. It induces p53-dependent antiproliferation and upregulates DR5 expression, making it a valuable tool for studying p53 reactivation and apoptosis in cancer cell lines and in vivo models.
CAS Number
922150-12-7
Product Name Alternative
P53, P53R3, P-53R3
Field of Research
Cell Biology
Purity
97.56% (May vary between batches)
Solubility
DMSO:90 mg/mL (151.88 mM)
Smiles
COC (=O) [C@@H] (Nc1nc (CN2CCN (CC2) C (c2ccc (Cl) cc2) c2ccc (Cl) cc2) nc2ccccc12) C (C) C
Molecular Formula
C32H35Cl2N5O2
Molecular Weight
592.56
Storage Conditions
-20°C
Notes
For research use only.

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