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GP 1a

CAT: 0013-GTR19188504-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19188504-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GP 1a is a potent and selective CB2 receptor agonist (EC50=7.1 nM) with demonstrated efficacy in cellular assays, including cAMP inhibition and ERK1/2 phosphorylation. It exhibits anti-inflammatory and anti-fibrotic properties, promoting epithelial regeneration, which supports its research application in models of skin wound healing and tissue repair.
CAS Number
511532-96-0
Product Name Alternative
GP 1a, CB2, Cannabinoid Receptor, CannabinoidReceptor, PERK
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.44% (May vary between batches)
Solubility
Ethanol:90 mg/mL (203.92 mM) ; DMSO:90 mg/mL (203.92 mM)
Smiles
C (NN1CCCCC1) (=O) C=2C3=C (N (N2) C4=C (Cl) C=C (Cl) C=C4) C=5C (C3) =CC (C) =CC5
Molecular Formula
C23H22Cl2N4O
Molecular Weight
441.35
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-(Piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide

1-(2,4-dichlorophenyl)-6-methyl-N-(1-piperidinyl)-4H-indeno[1,2-c]pyrazole-3-carboxamide is a member of pyrazoles and a ring assembly.

CAS Number511532-96-0
PubChem CID10252734
IUPAC Name1-(2,4-dichlorophenyl)-6-methyl-N-piperidin-1-yl-4H-indeno[2,1-d]pyrazole-3-carboxamide
Molecular FormulaC23H22Cl2N4O
Molecular Weight441.3
XLogP5.9
Topological Polar Surface Area50.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Heavy Atom Count30
Formal Charge0
Complexity630
SMILES
CC1=CC2=C(C=C1)C3=C(C2)C(=NN3C4=C(C=C(C=C4)Cl)Cl)C(=O)NN5CCCCC5
InChI
InChI=1S/C23H22Cl2N4O/c1-14-5-7-17-15(11-14)12-18-21(23(30)27-28-9-3-2-4-10-28)26-29(22(17)18)20-8-6-16(24)13-19(20)25/h5-8,11,13H,2-4,9-10,12H2,1H3,(H,27,30)
InChIKey
FNOMTMVRTBHRET-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(Piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide
CAS: 511532-96-0
CID: 10252734
Formula: C23H22Cl2N4O
MW: 441.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight441.3
XLogP35.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass440.1170667
Monoisotopic Mass440.1170667
Topological Polar Surface Area50.2 Ų
Heavy Atom Count30
Formal Charge0
Complexity630
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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