SENP2, CT (Sentrin SUMO-specific protease 2)

• NCBI Gene ID:

  59343

• Reactivity:

  Human, Mouse

• Storage Conditions:

  May be stored at 4 °C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 °C. Aliquots are stable for at least 12 months at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

• Specificity:

  Covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respect to size and ubiquity. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied extensively. Recently, a new group of ubiquitin-like proteins has been receiving a lot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicated in the stabilization of target proteins and/or their localization to sub-cellular complexes.

• Other Gene Names:

  [SENP2; SENP2; AXAM2; SMT3IP2; KIAA1331; DKFZp762A2316; KIAA1331]

• Short Name:

  [SENP2]

• Other Product Names:

  [sentrin-specific protease 2; Sentrin-specific protease 2; sentrin-specific protease 2; OTTHUMP00000210348; SMT3-specific isopeptidase 2; sentrin/SUMO-specific protease SENP2; SUMO1/sentrin/SMT3 specific protease 2; SUMO1/sentrin/SMT3 specific peptidase 2; Axam2; SMT3-specific isopeptidase 2; Smt3ip2; Sentrin/SUMO-specific protease SENP2]

• NCBI GI Number:

  54607091

• NCBI Accession Number:

  NP_067640.2

• NCBI GB Accession Number:

  NM_021627.2

• Uniprot Accession Number:

  Q9HC62