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TAPI-1

CAT: 0013-GTR19188296Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19188296Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TAPI-1 is a cell-permeable inhibitor of ADAM17/TACE that effectively blocks the ectodomain shedding of cytokine receptors and other transmembrane proteins. This small molecule is widely used in both in vitro and in vivo research to investigate inflammation, cancer, and signaling pathways dependent on regulated proteolysis.
CAS Number
163847-77-6
Product Name Alternative
Inhibitor, Matrix metalloproteinases, MMP, inhibit, cell surface proteins, ADAM17/TACE, TAPI, TAPI 1, TAPI1, TAPI-1, TAPI-1 Isomer
Field of Research
Protein Biochemistry
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.61 mM) ; Ethanol:92 mg/mL (184.15 mM) ; DMSO:92 mg/mL (184.15 mM) ; H2O:55 mg/mL (110.09 mM)
Smiles
CC (C) C[C@H] (CC (=O) NO) C (=O) N[C@@H] (Cc1ccc2ccccc2c1) C (=O) N[C@@H] (C) C (=O) NCCN
Molecular Formula
C26H37N5O5
Molecular Weight
499.6
Storage Conditions
-20°C
Notes
For research use only.

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