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PBRM1-BD2-IN-5

CAT: 0013-GTR19188265-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19188265-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PBRM1-BD2-IN-5 is a potent and selective small molecule inhibitor of the PBRM1 bromodomain 2 (BD2), with a Kd of 1.5 μM and an IC50 of 0.26 μM. It disrupts PBAF complex interactions with acetylated histones in cellular assays, making it a valuable chemical probe for oncology research targeting chromatin remodeling in cancer.
CAS Number
2819989-61-0
Product Name Alternative
EpigeneticReaderDomain, Epigenetic Reader Domain, PBRM1BD2IN5, PBRM1-BD2-IN-5
Field of Research
Epigenetics & Chromatin
Purity
99.51% (May vary between batches)
Solubility
DMSO:50 mg/mL (183.33 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.33 mM)
Smiles
O=C1C=2C (NC (N1) C3=CC (C) =CC=C3) =CC=CC2Cl
Molecular Formula
C15H13ClN2O
Molecular Weight
272.73
Storage Conditions
-20°C
Notes
For research use only.

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