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RP-6685

CAT: 0013-GTR19188254-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19188254-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RP-6685 is a potent, selective, and orally active DNA polymerase theta (Polθ) inhibitor with an IC50 of 5.8 nM. It demonstrates robust antitumor activity in mouse xenograft models, making it a valuable tool for investigating Polθ's role in DNA repair and oncology research, both in vitro and in vivo.
CAS Number
2832047-80-8
Product Name Alternative
RP 6685, RP6685, RP-6685, RNA Synthesis, RNASynthesis, DNASynthesis, DNA polymerase, DNA Synthesis
Field of Research
Cell Biology, Molecular Biology
Purity
98.34% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (6.63 mM) ; DMSO:112.5 mg/mL (226.19 mM)
Smiles
Nc1ccc (nn1) C#CCN (C (=O) Cc1ncc (cc1C (F) (F) F) C (F) (F) F) c1ccc (F) cc1
Molecular Formula
C22H14F7N5O
Molecular Weight
497.37
Storage Conditions
-20°C
Notes
For research use only.

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