Products for Research Use Only

Disulfamide

CAT: 0013-GTR19187910-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19187910-02Size:5 mg
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Description
Disulfamide is a potent, orally active carbonic anhydrase inhibitor (IC50 = 0.07 μM) . Its diuretic action stems from blocking sodium and bicarbonate reabsorption in renal proximal tubules, making it a useful research tool for studying renal physiology, hypertension, and enzyme inhibition in vitro and in vivo.
CAS Number
671-88-5
Product Name Alternative
Carbonic Anhydrase, Carbonic anhydrase, CarbonicAnhydrase
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.10% (May vary between batches)
Solubility
DMSO:45 mg/mL (158.04 mM)
Smiles
S (N) (=O) (=O) C1=CC (S (N) (=O) =O) =C (Cl) C=C1C
Molecular Formula
C7H9ClN2O4S2
Molecular Weight
284.74
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Disulfamide

Disulfamide is a sulfonamide.

CAS Number671-88-5
PubChem CID68935
IUPAC Name4-chloro-6-methylbenzene-1,3-disulfonamide
Molecular FormulaC7H9ClN2O4S2
Molecular Weight284.7
XLogP0
Topological Polar Surface Area137
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Heavy Atom Count16
Formal Charge0
Complexity450
SMILES
CC1=CC(=C(C=C1S(=O)(=O)N)S(=O)(=O)N)Cl
InChI
InChI=1S/C7H9ClN2O4S2/c1-4-2-5(8)7(16(10,13)14)3-6(4)15(9,11)12/h2-3H,1H3,(H2,9,11,12)(H2,10,13,14)
InChIKey
RCFKEIREOSXLET-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Disulfamide
CAS: 671-88-5
CID: 68935
Formula: C7H9ClN2O4S2
MW: 284.7
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight284.7
XLogP30
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass283.9692268
Monoisotopic Mass283.9692268
Topological Polar Surface Area137 Ų
Heavy Atom Count16
Formal Charge0
Complexity450
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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