Dynein, Cytoplasmic, 74kD Intermediate Chains

• Reactivity:

  Bovine, Drosophila, Mouse, Rat, Sheep, Xenopus

• Storage Conditions:

  May be stored at 4 °C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 °C. Aliquots are stable for at least 12 months at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

• Specificity:

  Recognizes all known forms of the Mr 74kD intermediate chain subunit (IC74) of mammaliam cytoplasmic dynein. The antigenic site has been localized to the first 60 amino acids of the amino terminal portion of the molecule (a region conserved in both IC74 genes). Species Crossreactivity: Rat, mouse, bovine, sheep, fish, Drosophila and Xenopus. Does not react with squid.

• Short Name:

  [Dynein, Cytoplasmic, 74kD Intermediate Chains]