Products for Research Use Only
RegisterLogin

Verosudil

CAT: 0013-GTR19188412-02Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19188412-02Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Verosudil (AR-12286) is a potent ROCK inhibitor with Ki values of 2 nM for both ROCK1 and ROCK2. It lowers intraocular pressure by enhancing trabecular meshwork outflow, as demonstrated in steroid-induced ocular hypertension models in mice, supporting research in glaucoma pathophysiology.
CAS Number
1414854-42-4
Product Name Alternative
AR 12286, AR12286, AR-12286, ROCK1, ROCK2, Verosudil
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.68% (May vary between batches)
Solubility
DMSO:45 mg/mL (137.45 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.05 mM)
Smiles
CN (C) C (C (=O) Nc1ccc2c (cc[nH]c2=O) c1) c1ccsc1
Molecular Formula
C17H17N3O2S
Molecular Weight
327.4
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Verosudil

a Rho kinase inhibitor

CAS Number1414854-42-4
PubChem CID66906051
IUPAC Name2-(dimethylamino)-N-(1-oxo-2H-isoquinolin-6-yl)-2-thiophen-3-ylacetamide
Molecular FormulaC17H17N3O2S
Molecular Weight327.4
XLogP2
Topological Polar Surface Area89.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count23
Formal Charge0
Complexity494
SMILES
CN(C)C(C1=CSC=C1)C(=O)NC2=CC3=C(C=C2)C(=O)NC=C3
InChI
InChI=1S/C17H17N3O2S/c1-20(2)15(12-6-8-23-10-12)17(22)19-13-3-4-14-11(9-13)5-7-18-16(14)21/h3-10,15H,1-2H3,(H,18,21)(H,19,22)
InChIKey
VDYRZXYYQMMFJW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Verosudil
CAS: 1414854-42-4
CID: 66906051
Formula: C17H17N3O2S
MW: 327.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight327.4
XLogP32
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass327.10414797
Monoisotopic Mass327.10414797
Topological Polar Surface Area89.7 Ų
Heavy Atom Count23
Formal Charge0
Complexity494
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA4488-5.1Verosudil
T70735-01Verosudil hydrochloride
HY-16758AVerosudil (hydrochloride)

Popular Products