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MK-2461

CAT: 0013-GTR19188246-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19188246-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MK-2461 is a potent, ATP-competitive small molecule inhibitor targeting multiple proteins, with notable activity against activated c-Met (IC50 = 2.5 nM) . It is widely used in cancer research, particularly in studies of tumor growth and metastasis, and has been applied in both in vitro cellular assays and in vivo xenograft models.
CAS Number
917879-39-1
Product Name Alternative
HGFR, MK2461, MK-2461, MK 2461, Inhibitor, inhibit, cMet, c-Met, c-Met (M1250T), c-Met (N1100), c-Met (Y1230C), c-Met (Y1230H), c-Met (Y1235D), c-Met/HGFR, cMet/HGFR
Field of Research
Signal Transduction
Purity
95.41% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.66 mM) ; DMSO:92 mg/mL (185.65 mM)
Smiles
CN (C[C@@H]1COCCO1) S (=O) (=O) Nc1ccc2ccc3ncc (cc3c (=O) c2c1) -c1cnn (C) c1
Molecular Formula
C24H25N5O5S
Molecular Weight
495.55
Storage Conditions
-20°C
Notes
For research use only.

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