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KT185

CAT: 0804-HY-114926-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114926-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KT185 is an orally-bioavailable, brain-penetrant and selective ABHD6 inhibitor, with an IC50 0.21 nM in Neuro2A cells[1].
CAS Number
1472640-86-0
Product Name Alternative
CI947
UNSPSC
12352005
Target
MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kt185.html
Purity
99.37
Solubility
DMSO : 30 mg/mL (ultrasonic; warming)
Smiles
O=C(N1N=NC(C2=CC=C(C=C2)C3=CC=CC(C(N4CCCCC4)=O)=C3)=C1)N5C(CCCC5)C6=CC=CC=C6
Molecular Formula
C32H33N5O2
Molecular Weight
519.64
References & Citations
[1]Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6) . J Med Chem. 2013 Nov 14;56 (21) :8270-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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