DNA PK, Catalytic Subunit (DNA-dependent Protein Kinase)

• NCBI Gene ID:

  5591

• Reactivity:

  Human, Rat

• Storage Conditions:

  May be stored at 4 °C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at-20 °C or colder. Aliquots are stable for at least 12 months at-20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

• Specificity:

  Inhibits ~50% of the kinase activity of DNAPKcs. Preincubation of enzyme with DNA protects DNA-PKcs against inactivation. Species Crossreactivity: human and rat.

• Other Gene Names:

  [PRKDC; PRKDC; HYRC; p350; DNAPK; DNPK1; HYRC1; XRCC7; DNA-PKcs; HYRC; HYRC1; DNA-PK catalytic subunit; DNA-PKcs]

• Short Name:

  [DNA PK, Catalytic Subunit]

• Other Product Names:

  [DNA-dependent protein kinase catalytic subunit isoform 1; DNA-dependent protein kinase catalytic subunit; DNA-dependent protein kinase catalytic subunit; p460; DNA-PK catalytic subunit; hyper-radiosensitivity of murine scid mutation, complementing 1; protein kinase, DNA-activated, catalytic polypeptide; DNPK1; p460]

• NCBI GI Number:

  13654237

• NCBI Accession Number:

  NP_008835.5

• NCBI GB Accession Number:

  NM_006904.6

• Uniprot Accession Number:

  P78527