14-3-3 Binding Motif, phosphorylated (Ser)

• NCBI Gene ID:

  7529

• Reactivity:

  Mammal

• Storage Conditions:

  May be stored at 4 °C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 °C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

• Specificity:

  Recognizes peptides/proteins containing phospho-Ser surrounded by Pro at the +2 position and Arg/Lys at the -3 position. By ELISA, recognizes a wide range of peptides containing this phosphorylated 14-3-3 binding motif in a manner that is phospho-specific and largely independent of the surrounding amino acid sequence. Weakly crossreacts with sequences containing phospho-Thr instead of phospho-Ser in this motif and with sequences containing phospho-Ser surrounded by Phe at the +1 position and Arg/Lys at the -3 position. No crossreactivity is observed with corresponding nonphosphorylated sequences.

• Other Gene Names:

  [YWHAB; YWHAB; HS1; GW128; YWHAA; KCIP-1; KCIP-1]

• Short Name:

  [14-3-3 Binding Motif]

• Other Product Names:

  [14-3-3 protein beta/alpha; 14-3-3 protein beta/alpha; 14-3-3 protein beta/alpha; 14-3-3 alpha; protein 1054; brain protein 14-3-3, beta isoform; protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; Protein 1054; Protein kinase C inhibitor protein 1]

• NCBI GI Number:

  21328448

• NCBI Accession Number:

  NP_647539.1

• NCBI GB Accession Number:

  NM_139323.3

• Uniprot Accession Number:

  P31946