b-Amyloid, NT

• Reactivity:

  Human

• Storage Conditions:

  May be stored at 4 °C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 °C. Aliquots are stable for at least 12 months at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

• Specificity:

  Specific for the N-terminal region of human amyloid- b. On Western blots, it identifies a band at 125kD (mature) and 110kD (immature). This antibody has been shown to recognize both the b'-cleavage-derived N-terminal ectodomain of APP (sAPPb') and the a-cleavage-derived N-terminal ectodomain of APP (sAPPa).8. Western blot utility has been confirmed with NT2N neurons, which are differentiated neurons derived from a NTera2 cell line.8

• Short Name:

  [b-Amyloid]