CD115 (c-fms, Fms, CSF-1R, M-CSFR)

• NCBI Gene ID:

  1436

• Reactivity:

  Human

• Storage Conditions:

  May be stored at 4 °C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 °C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

• Specificity:

  Recognizes proteins of 130kD & 150kD, identified as immature (gp130c-fms) and mature (gp150c-fms) forms of CD115. Blocks ligand binding and ligand-dependent proliferation. Inhibits CSF-1-independent growth of cells expressing mutant CSF-1R2. Species Crossreactivity: Human. Does not react with Mouse and feline.

• Other Gene Names:

  [CSF1R; CSF1R; FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R; FMS; CSF-1-R; CSF-1R; M-CSF-R]

• Short Name:

  [CD115]

• Other Product Names:

  [Colony stimulating factor 1 receptor; Macrophage colony-stimulating factor 1 receptor; macrophage colony-stimulating factor 1 receptor; CD115 antigen; CSF-1 receptor; FMS proto-oncogene; proto-oncogene c-Fms; macrophage colony stimulating factor I receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; colony stimulating factor 1 receptor; CSF-1 receptor (EC:2.7.10.1); CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD_antigen: CD115]

• NCBI GI Number:

  28833091

• NCBI Accession Number:

  AAH47521.1

• Uniprot Accession Number:

  P07333